How long does it take for Wegovy to work for weight loss?

The time it takes for Wegovy® (semaglutide) to work for weight loss can vary. One study showed that on average people lost ~6% of their starting body weight by 12 weeks, ~10% by 20 weeks, and ~15% at the one-year mark. Note that patients in the study used Wegovy in combination with healthy nutrition and physical activity. When starting a Wegovy prescription, patients start at the lowest dose (0.25 mg weekly) and gradually increase every 4 weeks to a maximum dose (2.4 mg weekly) as long as the medication is well tolerated. For some patients, there isn’t much of an effect at the lower dose, and weight loss may not start until they reach a higher dose of the medication.

How Long Should You Take Wegovy for Weight Loss?

Although Wegovy will start working for weight loss within the first few months of taking the medication, your weight loss efforts will be most successful if you continue taking it as you reach your weight loss goals and beyond. Continuing Wegovy after reaching your goal weight is recommended to maintain your achievement.

For more information on what it's like to take Wegovy, including how long it takes for Wegovy to work for weight loss, read this Wegovy week by week journal from a FORM patient.

Wegovy® is a registered trademark of Novo Nordisk A/S.

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Lauren Lemieux, MD

Lauren Lemieux, MD

FACP, ABOM diplomate

Dr. Lauren Lemieux completed her Internal Medicine residency and fellowship in Clinical Nutrition at UCLA. She is board certified in Internal Medicine and diplomate of the American Board of Obesity Medicine, and as a Physician Nutrition Specialist. She is also a fellow of the American College of Physicians. Dr. Lemieux is passionate about helping her patients reach their health goals using personalized nutrition, lifestyle and weight management strategies.