How Long Does It Take for Wegovy® (Semaglutide) to Work?

How long it takes for a person to start losing weight when taking Wegovy® for weight loss is dependent on many different factors, so there is not one answer for every person. One of the ways Wegovy helps with weight loss is to decrease appetite and cravings so a person can more easily reduce their calorie intake. Some notice an effect immediately after starting their medication while others do not experience appetite reduction until they get to higher doses.  Importantly, the dose must be gradually increased each month to avoid severe side effects, so even if it does not feel effective one should not prematurely increase the dose. Other factors that can affect weight loss progress include physical activity, quality of nutrition, sleep, stress, genetics and even our gut microbiome! On average, patients can expect to lose at least 5% of their starting body weight after taking the medication for 3 months if the medication is the right fit. If you feel like Wegovy is not working for you, it is important to discuss this with your medical provider.

Wegovy® is a registered trademark of Novo Nordisk A/S.

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Lauren Lemieux, MD

Lauren Lemieux, MD

FACP, ABOM diplomate

Dr. Lauren Lemieux completed her Internal Medicine residency and fellowship in Clinical Nutrition at UCLA. She is board certified in Internal Medicine and diplomate of the American Board of Obesity Medicine, and as a Physician Nutrition Specialist. She is also a fellow of the American College of Physicians. Dr. Lemieux is passionate about helping her patients reach their health goals using personalized nutrition, lifestyle and weight management strategies.