How does Zepbound (tirzepatide) work for weight loss?

Zepbound® is an injectable medication that is a combination GIP/GLP-1 receptor agonist. It is approved for weight loss in adults with a body mass index (BMI) of 30+ kg/m2 or 27+ kg/m2, with weight related medical problems such as high blood pressure, diabetes and high cholesterol, in combination with a low calorie diet and increased physical activity. It mimics two hormones our body naturally makes: GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 (glucagon-like peptide-1). GLP-1 acts on the pancreas to stimulate the release of insulin which lowers blood sugar and acts on the brain to decrease appetite and cravings. The addition of a GIP agonist to a GLP-1 agonist has been found to promote additional weight loss. In clinical trials, individuals who took tirzepatide for up to a year and a half lost an average of 26.6% of their body weight.

Learn more about how Form Health prescribes Zepbound  to help patients reach their weight loss goals.

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ABOUT THE AUTHOR

Form Health

Form Health is a virtual obesity medicine clinic founded in 2019 that provides science-based obesity care to help patients achieve their weight loss and health goals. Patients have the opportunity to achieve sustainable weight loss by working closely with an American Board of Obesity Medicine physician and a Registered Dietitian who is a Board Certified Specialist in Obesity and Weight Management. Each Care Team develops a personalized treatment plan based on a comprehensive review of their medical history that includes behavioral support, nutrition, physical activity, and medication, if appropriate.

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Zepbound® and its delivery device base are registered trademarks owned or licensed by Eli Lilly and Company, its subsidiaries, or affiliates.