Why is Contrave (naltrexone/bupropion) not working?

Some people do not notice the benefits of Contrave® for weight loss until they reach a higher dose, so give it time. Contrave is started at a low dose and increased slowly to reduce the potential for side effects.

If you’ve been taking Contrave at the highest recommended dose for 3 months and have not noticed a change in your appetite or at least a 5% weight loss, discuss alternative options with your healthcare professional. All weight loss medications affect people differently, so it’s not uncommon to take a medication but not get the results you’re expecting. The only way to know if a medication will work for you is to try it. Your healthcare professional may be able to recommend other options if the medication you’re taking is not working for you.

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ABOUT THE AUTHOR

Form Health

Form Health is a virtual obesity medicine clinic founded in 2019 that provides science-based obesity care to help patients achieve their weight loss and health goals. Patients have the opportunity to achieve sustainable weight loss by working closely with an American Board of Obesity Medicine physician and a Registered Dietitian who is a Board Certified Specialist in Obesity and Weight Management. Each Care Team develops a personalized treatment plan based on a comprehensive review of their medical history that includes behavioral support, nutrition, physical activity, and medication, if appropriate.

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Contrave® is a registered trademark of Currax Pharmaceuticals, LLC.