How Much Weight Can You Lose a Week on Wegovy® (Semaglutide)?

The amount of weight per week one loses on Wegovy® will vary from one patient to the next. Importantly, Wegovy is used in combination with lifestyle changes such as a reduced calorie diet and increased physical activity to promote weight loss. In this study, people lost on average of about 6% of their starting weight by 12 weeks, about 10% by 20 weeks, and about 15% by one year (a little more than 0.5 lb per week). Importantly, when starting a Wegovy prescription, patients begin at the lowest dose (0.25 mg weekly) and gradually increase every four weeks to a maximum dose of 2.4 mg weekly as long as the medication is well tolerated. For some patients, weight loss may not start until they reach a higher dose of the medication.

Wegovy® is a registered trademark of Novo Nordisk A/S.

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Nathaniel Pedley, MD

Nathaniel Pedley, MD

ABOM Diplomate

Dr. Nathaniel Pedley is an internist and obesity medicine specialist who is passionate about supporting patients in achieving their health goals. He attended Amherst College in Massachusetts for undergrad, and completed a post-baccalaureate in pre-medical studies at Columbia University. He continued at Columbia University for medical school and went on to complete his residency in internal medicine at UCLA where he served as a Project Lead for the UCLA Department of Medicine Quality Team and a peer mentor to junior residents.