Can You Take Orlistat With Saxenda®?

There are no known drug interactions between Orlistat and Saxenda.  However, Orlistat can interact with other drugs such as certain immunosuppressant medications and warfarin (Coumadin®) as well as impair the absorption of fat-soluble vitamins (A, D, E, and K).  Orlistat is a medication that is FDA-approved for weight loss and is available over-the-counter as Alli® and by prescription as Xenical®.  Orlistat works by blocking the absorption of dietary fat from foods thereby reducing calorie intake to facilitate weight loss.  In certain situations, combinations of weight loss medications might be recommended by your doctor.  Deciding whether or not to start a new medication (even if sold over-the-counter) should be discussed with your doctor. 

Learn more about Alli here and Xenixcal here.

Brooke Marsico, PA-C

Brooke Marsico, PA-C

About the Author
Brooke Marsico completed her physician assistant training at Midwestern University. Brooke is passionate about helping patients living with obesity achieve meaningful weight loss and improve their health.Learn more about Brooke here.

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