If you miss a dose of Foundayo™, take it as soon as possible. Do not take 2 doses of Foundayo on the same day. Do not take more than 1 tablet per day. If you miss taking Foundayo for 7 or more days in a row, call your prescribing clinician to talk about how to restart your treatment.
What is Foundayo?
Foundayo™, which contains the active ingredient orforglipron, is a once-daily oral tablet medication produced by Eli Lilly and approved by the FDA to treat obesity. Foundayo is used in conjunction with a reduced-calorie diet and increased physical activity to help adults with obesity, or some adults with overweight who have weight-related medical problems, lose excess body weight and keep it off. Foundayo is a small molecule, oral GLP-1 receptor agonist.


How does Foundayo work?
Foundayo (orforglipron) binds to and activates the human GLP-1 receptor. Foundayo acts on GLP-1 receptors in the appetite center of the brain, reducing appetite and food intake. GLP-1 also slows the process of stomach emptying, resulting in an earlier and prolonged sense of fullness. By reducing appetite and food intake, Foundayo reduces body weight.
In a 72 week clinical trial of adults without diabetes, those taking Foundayo, along with diet and exercise, lost about 25 pounds (~11% of body weight) on the highest dose of Foundayo, about 17 pounds (~7% of body weight) on the lowest studied dose of Foundayo, and about 5 pounds (~2% of body weight) with diet and exercise alone.
When would a Form Health clinician prescribe Foundayo?
Foundayo may be prescribed if you have a BMI of 30 or higher or 27 or higher with certain weight-related conditions, and you have not been successful in losing weight or maintaining weight loss with lifestyle changes alone. During a telehealth appointment, your Form Health clinician will carefully look at your medical history, the medicines you're taking, and lab results to see if FDA-approved medications like Foundayo are right for you. At Form, weight loss medications are used in combination with a personalized weight loss plan that addresses nutrition, physical activity, and mindset shifts. It’s this combination of medication and lifestyle change that has been proven to result in significant and sustained weight loss.
Foundayo can be prescribed by a Form Health clinician through telehealth, if appropriate. The cost of a Foundayo prescription will vary based on what insurance you have.
Who qualifies for Foundayo?
You may qualify for Foundayo if:
- you have a BMI of 30 or higher
- you have a BMI of 27 or higher with certain weight-related conditions
Please note that even if you meet BMI requirements, Foundayo may still not be appropriate for you. Your medical history, current medications, and insurance benefits will be taken into consideration during a discussion with your Form Health clinician prior to receiving a prescription.
Foundayo is an FDA-approved medication for weight loss that can be prescribed by your Form Health clinician.
How to get a Foundayo prescription online
4 steps to determining if Foundayo is right for you
Take the Form Health eligibility quiz
Our simple, 5 minute quiz helps determine if you meet the criteria for our medical weight loss program, and whether your insurance will cover Form Health program costs. Once you qualify, sign-up on the Form website and download our app.
Complete your onboarding paperwork
Fill out an online onboarding survey that collects information on your medical history, medications, and previous weight loss attempts so your clinical team can get to know you and personalize a weight loss plan for you.
Meet with your Form Health Board Certified Clinician
You will meet your Form Health clinician during your first virtual visit to discuss your personalized weight loss plan, which may include prescription medications like Foundayo, if appropriate. Your Foundayo prescription will be sent to your preferred pharmacy, whether local or online. You’ll meet with your clinician regularly and can always reach them via messaging so they can monitor for any side effects, make any adjustments needed, and provide support throughout your Form journey.
Meet with your Form Health Registered Dietitian
Together, you will set nutrition and exercise goals. Foundayo works best when paired with lifestyle changes!
Foundayo side effects
Although Foundayo offers numerous advantages, like any medication, it can have potential side effects. The primary side effects of Foundayo include:
- Nausea
- Constipation
- Diarrhea
- Vomiting
- Indigestion
- Stomach (abdominal pain)
- Headache
- Bloating
- Fatigue
- Belching
- Heartburn
- Gas
- Hair loss
These are not all the possible side effects of Foundayo. Talk to your healthcare provider about any side effects that bother you or don’t go away.

Frequently asked questions
about Foundayo
What happens if you miss a dose of Foundayo?
How long does it take Foundayo to work?
You may notice the effect of Foundayo as soon as you start taking it, but this will vary from person to person, with some individuals needing a higher dose to experience its effects.
You’ll take the starting dose of 0.8 mg for at least 30 days. The dose of the medication can be increased monthly up to a maximum of 17.2 mg daily. You will stay on a dose for a minimum of 30 days to give your body time to adjust and reduce the risk of severe side effects. Your clinician will work with you to determine what dose is right for you based on response and tolerability.
How long should you stay on Foundayo?
Foundayo is FDA-approved for chronic weight management, which means it is intended for long-term use as part of an ongoing treatment plan. It’s meant to help adults with obesity, or adults with overweight and at least one weight-related medical condition, reduce excess body weight and maintain weight loss over time when used with a reduced-calorie diet and increased physical activity.
Does Foundayo make you tired?
Foundayo can make some people feel tired, and fatigue is listed as a potential side effect of the medication. It is not the most common effect for everyone, but it has been reported as one of the possible symptoms people may notice while taking it.
Can you drink alcohol on Foundayo?
Drinking alcohol is generally not recommended when patients are taking Foundayo. Foundayo is intended for use in combination with a low-calorie eating pattern, and drinking alcohol can make it difficult to achieve a caloric reduction. Alcohol is not a calorie-free beverage, and by lowering inhibitions, it can lead to increased food consumption. It is important that you discuss your alcohol intake when taking Foundayo with your provider, as it may be advised to avoid alcohol completely.
Foundayo™ is a registered trademark owned or licensed by Eli Lilly and Company, its subsidiaries, or affiliates.

