Does Ozempic (semaglutide) cause headaches?

 

Yes, Ozempic® can cause headaches. Headaches are listed as a possible side effect on the drug manufacturer’s website. Though the frequency of headaches when starting Ozempic is not clear, 14% of those taking the maximum dose of Wegovy® which also contains semaglutide which is the main component of Ozempic, experienced headaches. This is compared to only 10% of those taking a placebo (something that has no therapeutic effect). Nonetheless, for most patients adverse reactions including headache tend to go away with time, and a review of the safety of semaglutide shows that medications like Ozempic are generally well tolerated, with early discontinuation rates - that is, stopping the medication early due to side effects - that are low and similar to those taking a placebo. Gastrointestinal symptoms such as nausea, vomiting, diarrhea, and constipation are the most common side effects of Ozempic.

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Form Health is a virtual obesity medicine clinic founded in 2019 that provides science-based obesity care to help patients achieve their weight loss and health goals. Patients have the opportunity to achieve sustainable weight loss by working closely with an American Board of Obesity Medicine physician and a Registered Dietitian who is a Board Certified Specialist in Obesity and Weight Management. Each Care Team develops a personalized treatment plan based on a comprehensive review of their medical history that includes behavioral support, nutrition, physical activity, and medication, if appropriate.

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Ozempic® is a registered trademark of Novo Nordisk A/S.