Is Trulicity (dulaglutide) the same as Ozempic (semaglutide)?

No, Trulicity® is not the same as Ozempic®, but there are some similarities. While both are in the same family or class of medications known as glucagon-like peptide-1 (GLP-1) receptor agonists, their active ingredients are different. Trulicity contains dulaglutide as its GLP-1 receptor agonist while Ozempic contains semaglutide. Both medications are FDA-approved to treat type 2 diabetes and work to lower blood sugar levels by stimulating the release of insulin by the pancreas. A study comparing different doses of Trulicity and Ozempic showed that Ozempic was more effective in lowering A1c and weight than Trulicity. It is important to note that Ozempic’s active ingredient, semaglutide, is also the active ingredient of Wegovy®, a medication that is FDA-approved to treat obesity. Wegovy demonstrated in clinical trials an average of 15% body weight loss at one year in people taking the maximum dose in combination with a low calorie diet and increased physical activity.

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Form Health is a virtual obesity medicine clinic founded in 2019 that provides science-based obesity care to help patients achieve their weight loss and health goals. Patients have the opportunity to achieve sustainable weight loss by working closely with an American Board of Obesity Medicine physician and a Registered Dietitian who is a Board Certified Specialist in Obesity and Weight Management. Each Care Team develops a personalized treatment plan based on a comprehensive review of their medical history that includes behavioral support, nutrition, physical activity, and medication, if appropriate.

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Disclaimer: The content made available on The Form Health Website represents the views and opinions of the authors and not those of other entities, such as the manufacturers of products mentioned therein.  
Trulicity® is a registered trademark of Eli Lilly and Company. Wegovy® and Ozempic® are registered trademarks of Novo Nordisk A/S.