Frequently asked questions about medical weight loss

Browse these FAQ's to find the answers common questions about medical weight loss programs. Learn how medical weight loss works, what makes it safe and effective, and more.

Does medical weight loss work?

Medical weight loss can work for individuals who are struggling to lose weight despite trying nutrition and lifestyle changes on their own or those who need medical supervision during their weight loss journey. Medical weight loss programs typically involve working with a team of healthcare providers such as a doctor, physician assistant, nurse practitioner, and/or Registered Dietitian. Together, they support patients with behavioral health, lifestyle changes and, if appropriate, may recommend medication for weight loss. When looking for a medical weight loss program, it can be helpful to first identify your unique needs and challenges. For example, if you struggle making healthier food choices and preparing meals, you would likely benefit from working with a program that includes regular visits with a Registered Dietitian. 

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Is medical weight loss safe?

Yes, under the guidance of the right medical team, medical weight loss is both safe and effective. Medical weight loss typically involves working with a multidisciplinary team (e.g. doctor, nurse practitioner, physician assistant, Registered Dietitian, psychologist/therapist). This team works with you to identify barriers to weight loss and consider your unique medical history to develop a personalized plan tailored to your needs. For some individuals, the plan  may focus on behavioral health and lifestyle changes. For others, when appropriate, medication may be recommended, if appropriate.  

Be wary of medical weight loss programs that offer medications that are not FDA-approved.  These medications, such as compounded “tirzepatide” and “semaglutide,” are not the same as branded versions (Zepbound® and Wegovy®) and have not undergone rigorous clinical testing for safety or efficacy. Although they are often available at a lower cost, it’s important to know that these compounded weight loss medications come with real risks

FDA-approved medications to support weight loss should be used under close medical supervision. It’s important that you can always get in contact with the clinician who is prescribing your medication and that you have regular follow-up visits with them after starting medications. If a program doesn’t provide ongoing care from the prescribing clinician, it creates safety concerns that should not be ignored.

Safe medical weight loss programs prioritize your health and safety by taking a comprehensive approach. This typically involves a review of your medical history, which may include requesting a copy of your medical record from your primary care provider. It’s important to meet with your prescribing clinician so they can better understand any health issues you may have, medications you are taking, and allergies to medications. Together, you will review your current nutrition and activity habits, identify barriers to losing weight, and prior attempts you’ve made to lose weight to create a personalized plan for weight loss that is specific to your needs. 

If appropriate, the clinician may also discuss medication options, carefully explaining potential side effects and risks so that you can make an informed decision about your treatment. While simply filling out a questionnaire and getting a medication prescribed and sent to you without having to meet with the prescribing clinician may seem convenient, it will not provide the level of care needed to ensure your safety. A full evaluation and informed discussion with your healthcare provider are key to minimizing risks and maximizing the impact of your weight loss journey.

Does thyroid medication cause weight loss?

Yes, thyroid medication that is prescribed for treatment of hypothyroidism (low thyroid function) can cause weight loss. Keep in mind that thyroid medication is intended to be used in individuals who have a need for thyroid replacement as their body is not making enough thyroid hormone on its own. The most common cause of this is an autoimmune disorder known as Hashimoto’s hypothyroidism

Thyroid medication should not be used by individuals with normal thyroid function for weight loss purposes. Excessive thyroid hormone intake can cause hyperthyroidism, leading to symptoms such as palpitations, irregular heartbeat, increased blood pressure, chest pain, anxiousness, tremors and insomnia. Long-term side effects include low bone mass (osteopenia and osteoporosis) and an increased risk for atrial fibrillation, heart failure and stroke.

Can blood pressure medication cause weight loss?

Yes, some blood pressure medications can cause weight loss. Diuretic blood pressure medications, often called “water pills,” help lower blood pressure by removing excess water and sodium from your body through urine. Even though body weight may decrease, the weight that is lost is “water weight” and not body fat. Weight loss resulting from body fat loss can provide metabolic benefits like improved blood sugar and cholesterol, losing water weight does not have this effect.  

However, there are other blood pressure medications that can cause weight gain. Calcium channel blockers, such as amlodipine and nifedipine, can have the side effects of fluid retention (typically in the legs and ankles) and constipation which might increase your weight. Beta-blockers are another class of blood pressure medications associated with weight gain due to their effects on energy metabolism (for example, by blocking the body’s ability to mobilize fat stores) and lowering energy expenditure.

If you are concerned about weight gain while taking blood pressure medication, we recommend that you speak with your prescribing provider. You may also consider working with a medical weight loss expert to create a personalized treatment plan that addresses weight gain caused by medication. 

Can cholesterol medication cause weight loss?

No, cholesterol-lowering medications do not typically cause weight loss. Statins, such as atorvastatin, pravastatin and rosuvastatin, are the most commonly used cholesterol-lowering medications. These medications work by reducing cholesterol production by the liver. They can reduce unhealthy LDL-cholesterol and triglyceride levels while increasing healthy HDL cholesterol levels. The most common side effect of statins is muscle pain, affecting 1-10% of people taking these medications.

In some rare cases, cholesterol-lowering medications may cause weight loss if a person is having significant side effects from the medication such as diarrhea, vomiting, and/or poor appetite. However, these side effects are uncommon. If you are experiencing these symptoms, it is important to discuss this with your prescribing provider.  

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Zepbound® and its delivery device base are registered trademarks owned or licensed by Eli Lilly and Company, its subsidiaries, or affiliates.

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