How long does Zepbound stay in your system?

Zepbound™ stays in your system for approximately 30 days after you stop the medication. This is based on the half-life of the medication which is 5 days. The half-life is the time it takes for half (50%) of the drug to be removed from your body. Keep in mind, the 5 day half-life is an estimate and it may vary from person to person. Due to its long half-life, Zepbound prescriptions can be administered once weekly. If you miss taking your Zepbound dose, administer the missed dose as soon as possible within 4 days. If it has been more than 4 days, skip the missed dose and administer the next dose on your usual injection day. You should not take two doses of the medication within 3 days of each other. Also, if it has been more than 2 weeks since your last dose, please consult your prescribing medical clinician before resuming use.

Lauren Lemieux, MD, FACP, DABOM
ABOUT THE AUTHOR

Lauren Lemieux, MD, FACP, DABOM

Dr. Lauren Lemieux completed her Internal Medicine residency and fellowship in Clinical Nutrition at UCLA. She is board certified in Internal Medicine and diplomate of the American Board of Obesity Medicine, and as a Physician Nutrition Specialist. She is also a fellow of the American College of Physicians. Dr. Lemieux is passionate about helping her patients reach their health goals using personalized nutrition, lifestyle and weight management strategies.

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Zepbound® and its delivery device base are registered trademarks owned or licensed by Eli Lilly and Company, its subsidiaries, or affiliates.