How long does Ozempic (semaglutide) stay in your system?

Ozempic® stays in your system for a little over a month when taken at the highest dose of 2 mg.  This is based on the half-life of the medication which is the time it takes for 50% of the drug to be removed.  The half life of Ozempic is 1 week, so if you take 2 mg on Monday the following Monday you’ll have 1 mg (half the dose) in your system.  One week later there will be 0.5 mg and so on.  As Ozempic is long-acting, it can be dosed once a week and maintain adequate drug levels in the body rather than having to take it daily.  If you miss taking your Ozempic within 5 days after your dose was due, you can still resume at the same dose. However, if longer than that time has elapsed, it is advised that you contact your doctor for how to proceed.

Learn more about Ozempic here.

Ozempic® is a registered trademark of Novo Nordisk A/S.

Lauren Lemieux, MD

Lauren Lemieux, MD

FACP, ABOM diplomate

Dr. Lauren Lemieux completed her Internal Medicine residency and fellowship in Clinical Nutrition at UCLA. She is board certified in Internal Medicine and diplomate of the American Board of Obesity Medicine, and as a Physician Nutrition Specialist. She is also a fellow of the American College of Physicians. Dr. Lemieux is passionate about helping her patients reach their health goals using personalized nutrition, lifestyle and weight management strategies.

Get started

Take our 3 minute quiz to see if you qualify.

Am I a Candidate?

More questions?
Schedule a free 15 minute call with an enrollment specialist.

Schedule a call